Furthermore, we also showed that appropriate physicochemical properties of wound dressing material such as porous structure, thickness/density, tensile strength and moisture-vapor transmission rate contributed to improve performance of wound dressing material. In our previous report, we showed that our wound dressing, Medifoam® N, has excellent physicochemical properties when compared with other dressing materials. The physical property of foam dressing should be maintained when it is coated with silver. Modern silver dressings should maintain moisture balance by absorbing excess exudate and preventing the wound drying out, while conferring antibacterial protection in wounds at risk of infection. Many reports describe that silver-based dressings are helpful to overcome bacterial infections, to promote environment for granulation/re-epithelialization in wound area, reduce adverse effects and to facilitate wound healing. Since silver-compounds such as silver nitrate and silver sulfadiazine is known to have antibacterial activity, it has been widely used in wound healing treatment as a silver-containing dressings or topical creams. However, these agents normally require frequent application, care-intensive application/removal, and cause painful reaction in patients. Topical silver creams and solutions have been extensively used for wound healing since they offer a broad spectrum of antimicrobial activity, less development of resistance, fewer adverse reactions, and a low risk of systemic toxicity. Due to potential bacterial resistance, topical use of antibiotics for non-infected wound is discouraged but still it is very commonly used. Wound infection commonly occurs from inappropriate cleansing, debridement, dressing techniques as well as exposure to contaminated sources, and represents a major barrier to wound healing. Subsequently, the balanced moist environment at the wound interface is known to facilitate closure and fast healing process. Furthermore, the absorption/retention performance of wet wound dressing material drives absorption of exudate and plays an important role in moisturized wound environment. Wet wound dressings may provide optimal conditions not only for proliferation of healthy cells but also for bacterial growth. The benefits of an optimal moist environment at the wound interface in terms of facilitating wound closure and spending up the healing process are well described. The aim of wound dressings is to promote tissue regeneration and ultimately to speed up wound healing, to reduce infections and minimize pain. So your patients experience less pain during dressing changes. Mepilex Ag adheres gently with Safetac ® – the original less-pain contact layer with silicone adhesion. And acts as an antimicrobial barrier in wounds at high risk of infection or re-infection. An international consensus has concluded that an antimicrobial action is indicated to help reduce bioburden in infected wounds. This silver foam dressing can inactivate wound relevant pathogens (bacteria and fungi) within 30 minutes, as shown in vitro. So you can use it to treat leg and foot ulcers, pressure ulcers and partial thickness burns. It’s designed for low to medium exuding burns and wounds. Mepilex ® Ag is our versatile antimicrobial foam dressing – for when you need an antimicrobial action to reduce bioburden in the wound.
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